Dynamics of the dosage of citrate-calciuminfusion regimens as anticoagulation in continuous venovenous hemodiafiltration
نویسندگان
چکیده
Methods A descriptive and comparative study about a prospective data basis is made. All the patients with CRRT requirements, admitted in ICU from September 2014 to March 2015 are included. Variables as motive of therapy, daily dosage of the therapy, days of therapy, half-life of systems on the first three days, global half-life of systems, type of anticoagulation, daily mean dosage of citrate-calcium, number of daily changes in these dosages and complications are analysed. The number of changes of citratecalcium and the day of therapy is compared, such as the filter’s length and the kind of anticoagulation.
منابع مشابه
A practical citrate anticoagulation continuous venovenous hemodiafiltration protocol for metabolic control and high solute clearance.
Obstacles to the widespread use of continuous renal replacement therapy (CRRT) include the need for anticoagulation, customized solutions, and complex protocols that carry an attendant risk for error, raise cost, and increase pharmacy and nursing workload. However, high solute clearance using CRRT with an effluent rate of 35 ml/kg per h has also recently been associated with improved survival i...
متن کاملIonized Magnesium and Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy.
BACKGROUND The regional citrate anticoagulation (RCA) induces changes in total (Catot) and ionized (Ca2+) calcium. As of now, we do not have much information about parallel changes of total (Mgtot) and ionized (Mg2+) magnesium. METHODS The authors compared changes of Mg2+ and Mgtot with changes of Ca2+ and Catot in 32 critically ill patients on 4% trisodium citrate (4% TSC) with calcium-free ...
متن کاملCitrate confers less filter-induced complement activation and neutrophil degranulation than heparin when used for anticoagulation during continuous venovenous haemofiltration in critically ill patients
BACKGROUND During continuous venovenous haemofiltration (CVVH), regional anticoagulation with citrate may be superior to heparin in terms of biocompatibility, since heparin as opposed to citrate may activate complement (reflected by circulating C5a) and induce neutrophil degranulation in the filter and myeloperoxidase (MPO) release from endothelium. METHODS No anticoagulation (n = 13), unfrac...
متن کاملIonized Magnesium and Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy
Background: The regional citrate anticoagulation (RCA) induces changes in total (Ca tot ) and ionized (Ca 2+ ) calcium. As of now, we do not have much information about parallel changes of total (Mg tot ) and ionized (Mg 2+ ) magnesium. Methods: The authors compared changes of Mg 2+ and Mg tot with changes of Ca 2+ and Ca tot in 32 critically ill patients on 4% trisodium citrate (4% TSC) with c...
متن کاملRegional Anticoagulation with Citrate is Superior to Systemic Anticoagulation with Heparin in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration
BACKGROUND/AIMS Short hemofilter survival and anticoagulation-related life-threatening complications are major problems in systemic anticoagulation with heparin (SAH) for continuous renal replacement therapy (CRRT). The present study examined if regional anticoagulation with citrate (RAC) using commercially available solutions can overcome the associated problems of SAH to produce economical be...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2015